Huberman Lab
Huberman Lab

Essentials: Using Hypnosis to Enhance Mental & Physical Health & Performance | Dr. David Spiegel

November 27, 2025 • 34m

Summary

⏱️ 9 min read

Overview

Dr. David Spiegel, Stanford professor of psychiatry, explains the science and clinical applications of hypnosis in this comprehensive discussion. He demystifies hypnosis as a state of highly focused attention that can be used therapeutically for pain, stress, trauma, sleep, and various mental health challenges. The conversation explores the neuroscience behind hypnosis, how it differs from stage hypnosis, assessment of hypnotizability, and practical applications including self-hypnosis techniques.

Understanding Hypnosis: Beyond the Stage Show Myths

Dr. Spiegel defines hypnosis as a state of highly focused attention, comparable to looking through a telephoto lens where you see details without context. He distinguishes clinical hypnosis from stage hypnosis, emphasizing that therapeutic hypnosis enhances rather than diminishes personal control. The state resembles getting absorbed in a movie where you forget you're watching and become part of the experience itself.

  • Hypnosis is a state of highly focused attention, like looking through a telephoto lens in consciousness
  • Getting absorbed in a movie to the point of forgetting you're watching is a hypnotic-like experience
  • Stage hypnosis makes fools of people and misrepresents the therapeutic potential of hypnosis
  • Clinical hypnosis enhances control over mind and body rather than taking it away
" You're gaining control. Self-hypnosis is a way of enhancing your control over your mind and your body. "
" It is that very ability to suspend critical judgment and just have an experience and see what happens. It's an ability that if people learn to recognize and understand it can be a tremendous therapeutic tool. "

The Neuroscience of Hypnosis: Brain Networks and Changes

Dr. Spiegel describes three key brain changes during hypnosis based on neuroimaging research. Activity decreases in the dorsal anterior cingulate cortex (conflict detector), functional connectivity increases between the dorsolateral prefrontal cortex and insula (enabling mind-body control), and inverse connectivity occurs between the DLPFC and posterior cingulate cortex (reducing self-reflection). These changes explain how hypnosis enables enhanced control over typically automatic bodily functions.

  • The dorsal anterior cingulate cortex activity decreases, reducing distractions and conflict detection
  • Increased DLPFC-insula connectivity enables mind-body control over functions like gastric acid secretion
  • Study showed hypnotized subjects increased gastric acid secretion by 87% through imagination alone
  • Inverse DLPFC-posterior cingulate connectivity creates dissociation, allowing action without self-reflection
  • Decreased posterior cingulate activity is similar to meditation, enabling selfless experience
" We found that they increased their gastric acid secretion by 87%. Their stomach was acting as though it was about to get... There was one woman it was so vivid for her that halfway through she said, let's stop, I'm full. "
" The brain has this amazing ability to control what's going on in the body in ways that we don't think we have ability to control. "

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