On Purpose with Jay Shetty

On Purpose with Jay Shetty

by Perfect Strangers

Jay Shetty hosts some of culture’s most influential voices in wellness and personal growth, helping you feel healthier, happier and more healed.

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Recent Episodes

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A deeply calming meditation designed for late-night listening, this episode guides listeners through releasing anxiety about the future using the metaphor of a person breaking stone. Jay Shetty explores how meaningful change happens gradually beneath the surface, encouraging patience with oneself and trust in the unknown. The episode weaves together visualization exercises, breathing techniques, and philosophical reflections on how the best moments in life arrive unannounced, ultimately helping listeners find peace before sleep.

  • Understanding Your Late-Night Mind
  • The Parable of Breaking Stone

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Dr. Joe Dispenza returns for his fourth appearance on On Purpose to discuss the neuroscience of transformation and how people can rewire their brains, heal their bodies, and create new realities through meditation and consciousness. He shares groundbreaking research showing how seven-day retreats produce measurable biological changes, including gene expression, tissue regeneration, and anti-viral properties in meditators. The conversation explores practical techniques for breaking free from past conditioning, overcoming limiting beliefs, and using focused intention combined with elevated emotion to literally transform one's biology and life circumstances.

  • Why People Seek Transformation and Wholeness
  • How Beliefs Actually Change Your Reality

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Jay Shetty explores why some people remain happy despite life's challenges while others stay stuck in unhappiness. He reveals three key mindset shifts happy people make: believing in their agency to influence outcomes, refusing to postpone joy until conditions are perfect, and actively designing daily moments of happiness. The episode challenges listeners to stop living as victims of circumstance and instead participate in creating their own joy through intentional choices and practices.

  • The Victim Mindset vs. Agency
  • Separating Events from Identity

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Simone Ashley joins Jay Shetty for an intimate conversation about her journey from awkward teenager to Bridgerton star, navigating life in New York, pursuing music, and manifesting love. She shares profound insights on self-belief, friendship, handling rejection in work versus relationships, and finding peace while feeling behind in life. The conversation explores her debut EP 'Songs I Wrote in New York,' the importance of non-materialistic values instilled by her mother, and the difference between being alone and being lonely.

  • From London to New York: Finding Home and Community
  • The Bridgerton Call That Changed Everything

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In this deeply personal conversation, actress Camila Mendes opens up about her journey through perfectionism, eating disorders, and finding peace through spirituality and therapy. She discusses her seven-year experience on Riverdale, the panic attacks and pressure that came with it, and how the Hoffman Institute transformed her relationship with herself. Camila shares intimate details about building a home with fiancé Rudy Mancuso, healing from past relationships, navigating her Brazilian-American identity, and preparing for her role in Masters of the Universe. Throughout, she emphasizes the importance of honesty, doing inner work, and learning to accept both the light and dark parts of ourselves.

  • Building Home and Finding Groundedness
  • The Challenge of Balancing Everything

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Jay Shetty explores why healthy couples fight and how to navigate conflict constructively in relationships. He emphasizes that conflict is inevitable and necessary in healthy partnerships, explaining that the goal isn't to eliminate disagreements but to learn how to move through them without destroying the relationship. The episode covers topics like emotional flooding, nervous system responses, communication patterns, the importance of repair, and why conflict avoidance can be just as damaging as explosive arguments.

  • The Reality of Conflict in Healthy Relationships
  • Understanding the Root Causes of Conflict

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Kiki Palmer opens up about her journey from child stardom to self-discovery, discussing how she found purpose through mindfulness practices, the challenges of growing up in the entertainment industry, and what she's learned about authenticity, boundaries, and love. She reveals the tools she developed to survive success, the moment she learned to put herself first, and how becoming a mother has reconnected her with her truest self.

  • Finding Authenticity Through Uncomfortable Feelings
  • Lessons From Motherhood and Setting Boundaries

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NBA champion Carl Anthony Towns joins the podcast for a deeply personal conversation about winning the championship with the New York Knicks, dealing with the loss of his mother and eight family members during COVID, his philosophy on life and basketball, and the importance of staying present. Towns opens up about his relationship with fiancée Jordan Woods, the famous orange bag lucky charm, stepping into his mother's shoes as head of the household, and how treating people right matters more than anything else.

  • The Championship Journey and Staying Present
  • Childhood Lessons and Standing Up to Authority

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Jay Shetty explores how one year of consistent bravery can transform your life. He explains that courage isn't a personality trait but a learnable skill built through repetition. The episode focuses on overcoming fear-based avoidance patterns, taking small courageous actions consistently, and understanding that your nervous system can't always distinguish between danger and growth. Jay provides practical frameworks for building courage through 'reps' rather than waiting to feel ready.

  • The Hidden Cost of Avoidance
  • Understanding Your Brain's Fear Response

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Jake Shane joins Jay Shetty for an intimate conversation about navigating sudden fame, mental health struggles, dating as a gay man in the public eye, and finding fulfillment beyond external validation. Jake opens up about his OCD, body image journey, fear of being perceived as a bad person, and the loneliness of modern dating while managing his rapidly growing platform.

  • Confusion and Fulfillment in Success
  • Journaling as a Safe Space and OCD Struggles

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Millie Bobby Brown joins Jay Shetty for an intimate conversation about motherhood, marriage to Jake Bongiovi, her adoption journey, battling anxiety and health anxiety, growing up as a child actor, and how she's building a life centered around family and authenticity. She opens up about finding peace through meditation in Japan, the importance of speaking your mind, and creating a strong foundation with her husband while blocking out public scrutiny.

  • Growing Up in the Spotlight and Defining Moments
  • The Transformative Power of Motherhood Through Adoption

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Jay Shetty explores the psychology of letting go and starting over in life, examining why we cling to identities and situations we've outgrown. Drawing on psychological concepts like loss aversion, the sunk cost fallacy, and narrative identity, he provides a framework for recognizing when it's time to move on, how to evaluate whether a risk is worth taking, and how to begin a new chapter without bitterness toward the past.

  • The Real Challenge: Letting Go vs. Starting Over
  • Why We Hold On: Loss Aversion and Sunk Cost Fallacy

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Across memorable conversations with guests including Selena Gomez, Kevin Hart, Kim Kardashian, Madonna, Kobe Bryant, Tom Holland, Emma Watson, and Mel Robbins, this special collection brings together ...

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This compilation episode brings together powerful conversations from On Purpose's most impactful interviews over the years. Jay Shetty explores themes of love, relationships, mental health, spirituality, friendship, and personal growth with guests including Benny Blanco and Selena Gomez, Kevin Hart, Madonna, Emma Watson, Kobe Bryant, and Michelle Obama. Each segment offers wisdom on navigating fame, finding purpose, building meaningful connections, and living with intention.

  • Benny Blanco and Selena Gomez on Finding True Love
  • Kevin Hart on Fame as a Drug and Finding Groundedness

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Success isn't always about having the best idea, it's about moving before fear, perfectionism, or conventional thinking slow you down. In this conversation, Jay sits down with entrepreneur and investo...

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Lucy Guo, entrepreneur, investor, and co-founder of Scale.ai, shares her unconventional path to becoming one of the youngest self-made female billionaires. She discusses why college is still valuable but not for traditional reasons, the importance of speed over perfection, and how AI is democratizing entrepreneurship. Lucy challenges conventional wisdom about hiring, decision-making, and success while offering practical insights on building companies in the AI era.

  • Rethinking College: Network Over Degrees
  • The Delusion Required for Entrepreneurship

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What if we've been thinking about mental illness all wrong? Harvard psychiatrist Dr. Chris Palmer argues that conditions like anxiety, depression, bipolar disorder, and schizophrenia may be rooted in ...

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In this episode, psychiatrist Dr. Chris Palmer discusses his groundbreaking work connecting metabolic health to mental illness. He explains how diet, particularly ultra-processed foods, impacts brain function and mental health conditions ranging from anxiety to schizophrenia. Palmer shares his personal journey inspired by his mother's struggle with psychosis and presents evidence for using metabolic interventions like ketogenic diets to treat severe mental illnesses, challenging traditional psychiatric approaches.

  • The Senate Address and Chronic Disease Epidemic
  • Diet's Overlooked Role in Mental Health

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Ten years after the loss of her husband, neurosurgeon and bestselling author Paul Kalanithi, Dr. Lucy Kalanithi reflects on how grief continues to evolve rather than disappear. In this deeply moving c...

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Dr. Lucy Kalanithi joins Jay Shetty to explore grief, loss, and living fully ten years after losing her husband, neurosurgeon and author Paul Kalanithi. Lucy shares intimate reflections on navigating terminal illness, choosing to have a child while facing death, reimagining how we approach dying in America, and finding meaning in suffering. The conversation delves into practical wisdom about supporting grieving loved ones, the neuroscience of loss, palliative care, and how witnessing death can transform how we live.

  • Remembering Paul: Life as Moments, Not Mountains
  • The Power of Presence and Description in Grief

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In one of her most honest conversations yet, Layla Taylor reflects on the quiet journey of becoming herself. She opens up about coming out as bisexual, navigating faith, identity, single motherhood, a...

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Leila Taylor, star of The Secret Lives of Mormon Wives, makes her first public coming out as bisexual in this deeply personal conversation. She opens up about her journey through childhood as a Black girl in predominantly white Utah, converting to Mormonism at 16, becoming a mother at 19, navigating a toxic marriage and divorce, and ultimately finding the courage to live authentically. Through moments of financial struggle as a single mom and years of suppressing her sexuality, Leila shares how becoming a mother inspired her to embrace every part of herself and step into a new chapter of authenticity.

  • Coming Out: Finding the Courage to Be Authentic
  • Growing Up Black in Predominantly White Utah

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Some endings hurt because they leave us with unanswered questions. After a breakup, it’s natural to search for reasons, replay memories, and hope for one final conversation that will make everything m...

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Jay Shetty delivers a compassionate and psychologically-grounded guide to healing from heartbreak, explaining why closure must come from within rather than from an ex-partner. He explores the neuroscience of romantic rejection, debunks the myth that more information leads to healing, and provides practical strategies for moving through grief toward genuine acceptance and personal growth.

  • The Trap of Seeking External Closure
  • The Neuroscience of Heartbreak

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For decades, we’ve been told that success and spirituality live in separate worlds. One is about achievement, the other about inner peace. In this conversation, John Mackey shares why he believes the ...

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John Mackey, co-founder and former CEO of Whole Foods Market, shares his spiritual journey from psychedelic awakening to building a conscious business empire. He discusses how Eastern philosophy, ego death experiences, and the concept of life as a 'dream' shaped his approach to leadership. Mackey reveals the challenges of selling Whole Foods to Amazon, his philosophy on servant leadership, and how purpose and love are the keys to employee retention. The conversation weaves together spirituality, capitalism, and practical business wisdom, offering a unique perspective on integrating consciousness into entrepreneurship.

  • Spiritual Awakening and the Path to Entrepreneurship
  • Understanding Ego Death and the Dream of Life

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Today Jay sits down with former First Lady Dr. Jill Biden where she pulls back the curtain on an extraordinary journey of love, profound loss, and unrelenting public scrutiny. After first rejecting a ...

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Dr. Jill Biden shares deeply personal stories spanning her life from meeting Joe Biden through their 49-year marriage, including navigating devastating losses, addiction in the family, political campaigns, and her time as First Lady. She reflects on teaching as her calling, building family on love and laughter, losing her stepson Beau to cancer, supporting Hunter through addiction, the 2024 debate that changed everything, and finding resilience through unimaginable grief.

  • Meeting Joe Biden and Building a Blended Family
  • Life-Threatening Health Crisis and Family Resilience

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